Clozapine-induced Gastrointestinal Hypomotility — New Objective Evidence for an Underestimated Side-effect
نویسندگان
چکیده
منابع مشابه
Clozapine-induced Gastrointestinal Hypomotility--New Objective Evidence for an Underestimated Side-effect.
Available online 27 February 2016 serum levels and (3) that this hypomotilitywas not reported by patients by themeans of subjective constipation symptoms. Remarkably, CTTs in clozapine were four times longer than for other antipsychotics or population norms and 4 of 5 clozapine-treated patients showed clear Clozapine is still the most effective antipsychotic drug in the manhypomotility (Every-P...
متن کاملDisorders of gastrointestinal hypomotility
Ingestion and digestion of food as well as expulsion of residual material from our gastrointestinal tract requires normal propulsive, i.e. motor, function. Hypomotility refers to inherited or acquired changes that come with decreased contractile forces or slower transit. It not only often causes symptoms but also may compromise nutritional status or lead to other complications. While severe for...
متن کاملClozapine-treated Patients Have Marked Gastrointestinal Hypomotility, the Probable Basis of Life-threatening Gastrointestinal Complications: A Cross Sectional Study.
BACKGROUND Gastrointestinal side effects are particularly common with clozapine and occur with other antipsychotics, ranging from mild constipation to fatal bowel obstruction and/or ischemia. While this adverse-effect spectrum has been attributed to 'gastrointestinal hypomotility', gastrointestinal transit times in antipsychotic-treated patients have not previously been measured, making this me...
متن کاملClozapine-induced acute gastrointestinal necrosis: a case report
BACKGROUND Clozapine is known to cause fecal impaction and ileus with resultant colonic necrosis due to compression of colonic mucosa. There are rare reports of clozapine causing necrosis of other portions of the gastrointestinal tract unrelated to constipation. We describe a case of acute necrosis of the upper gastrointestinal tract and small bowel to due to clozapine and quetiapine. CASE PR...
متن کاملDisorders of gastrointestinal hypomotility [version 1; referees: 2 approved]
Ingestion and digestion of food as well as expulsion of residual material from our gastrointestinal tract requires normal propulsive, i.e. motor, function. Hypomotility refers to inherited or acquired changes that come with decreased contractile forces or slower transit. It not only often causes symptoms but also may compromise nutritional status or lead to other complications. While severe for...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: EBioMedicine
سال: 2016
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2016.02.037